W Kalow

Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes.

Monica Campbell, Denis M. Grant, T. Inaba et al. · Drug Metabolism and Disposition · 1987 · 210 citations

Medicine, Pharmacology, Toxicology +17

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase.

T. Inaba, M Jurima, W. A. Mahon et al. · Drug Metabolism and Disposition · 1985 · 180 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6.

Rachel F. Tyndale, Roger K. Sunahara, T. Inaba et al. · Molecular Pharmacology · 1991 · 126 citations

Medicine, Neuroscience, Pharmacology +15

Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone.

D. Wu, S V Otton, U. Busto et al. · British Journal of Clinical Pharmacology · 1993 · 100 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole

Aleksandra Pastrakuljic, Bing Tang, Eve A. Roberts et al. · Biochemical Pharmacology · 1997 · 80 citations

Medicine, Pharmacokinetics, Pharmacology +11