Asha Ramanunni

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765

Sarah E. M. Herman, Amber Gordon, Erin Hertlein et al. · Blood · 2011 · 791 citations · Full text

Medicine, Oncology, Pharmacology +15

Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals

Rosa Lapalombella, Yuh-Ying Yeh, Liwen Wang et al. · Cancer Cell · 2012 · 139 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase–dependent pathway

Rosa Lapalombella, Leslie A. Andritsos, Qing Liu et al. · Blood · 2009 · 118 citations

Life Sciences, Hematology, Immunology +13

Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells

Rosa Lapalombella, Bo Yu, Georgia Triantafillou et al. · Blood · 2008 · 110 citations · Full text

Medicine, Immunology, Pharmacology +17

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro

Aruna Gowda, Julie M. Roda, Syed-Rehan A. Hussain et al. · Blood · 2008 · 100 citations · Full text

Life Sciences, Cell Biology, Oncology +10