Jan Molinský

Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL

Tabea Erdmann, Pavel Klener, James T. Lynch et al. · Blood · 2017 · 105 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma

Magdalena Klánová, Ladislav Anděra, Jan Bražina et al. · Clinical Cancer Research · 2015 · 100 citations

Medicine, Hematology, Oncology +15

B-cell receptor–driven MALT1 activity regulates MYC signaling in mantle cell lymphoma

Beiying Dai, Michael Grau, Mélanie Juilland et al. · Blood · 2016 · 74 citations · Full text

Medicine, Cancer Biology, Oncology +14

Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents

Magdalena Klánová, Lucie Lorková, Ondřej Vít et al. · Molecular Cancer · 2014 · 35 citations · Full text

Medicine, Oncology, Pharmacology +16

The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms

Lenka Beranová, António Pombinho, Jarmila Stremenova Spegarova et al. · APOPTOSIS · 2013 · 30 citations

Medicine, Oncology, Pharmacology +17