Yuna M. Ayala

A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing

Ailin Wang, Alexander E. Conicella, Hermann Broder Schmidt et al. · The EMBO Journal · 2018 · 468 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +6

TDP-43 α-helical structure tunes liquid–liquid phase separation and function

Alexander E. Conicella, Gregory L. Dignon, Gül H. Zerze et al. · Proceedings of the National Academy of Sciences · 2020 · 406 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation

Rachel L. French, Zachary R. Grese, Himani Aligireddy et al. · Journal of Biological Chemistry · 2019 · 129 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Specific RNA interactions promote TDP-43 multivalent phase separation and maintain liquid properties

Zachary R. Grese, Alliny C.S. Bastos, Lohany D. Mamede et al. · EMBO Reports · 2021 · 129 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

Xiao Yan, David Kuster, Priyesh Mohanty et al. · Cell · 2025 · 97 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17