James Messing

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

Peiguo Yang, Cécile Mathieu, Regina‐Maria Kolaitis et al. · Cell · 2020 · 1.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles

Kyung‐Ha Lee, Peipei Zhang, Hong Joo Kim et al. · Cell · 2016 · 728 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

Ian R. Mackenzie, Alexandra M. Nicholson, Mohona Sarkar et al. · Neuron · 2017 · 651 citations · Full text

Life Sciences, Neurology, Neuroscience +16

Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice

Lindsay A. Becker, Brenda Huang, Gregor Bieri et al. · Nature · 2017 · 583 citations

Education, Neurobiology, Neuroscience +11

Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology

Peipei Zhang, Baochang Fan, Peiguo Yang et al. · eLife · 2019 · 269 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17