Analysis of shared heritability in common disorders of the brain

Verneri Anttila, Brendan Bulik‐Sullivan, Hilary K. Finucane, +565

Science

Brain FunctionPsychiatric DisordersGeneticsGenetic EpidemiologyNeuropsychiatry +21

Brain charts for the human lifespan

Richard A. I. Bethlehem, Jakob Seidlitz, Simon R. White, +197

Nature

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Stephan Ripke, Colm Ó'Dúshláine, Kimberly Chambert, +58

Nature Genetics

Genome-wide Association StudyPsychiatryPsychotic DisorderGeneticsPsychiatric Genetics +7

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, Jian Yang, Hilary K. Finucane, +393

The American Journal of Human Genetics

Linkage DisequilibriumEngineeringPolygenic RiskRisk ManagementPolygenic Risk Scores +2

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Phil H. Lee, Verneri Anttila, Hyejung Won, +597

Cell

PsychiatryPsychiatric DisordersGenetic DisorderGeneticsPsychiatric Genetics +13

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Pamela Sklar, Stephan Ripke, Laura J. Scott, +165

Nature Genetics

Genome-wide Association StudyGenotype-phenotype AssociationPsychiatryGeneticsPsychiatric Genetics +6

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

Manuel A. R. Ferreira, Michael O’Donovan, Yan Meng, +58

Nature Genetics

Genome-wide Association StudyPsychiatryGeneticsPsychiatric GeneticsGenetic Epidemiology +3

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Christian R. Marshall, Daniel P. Howrigan, Daniele Merico, +259

Nature Genetics

PsychiatryGeneticsPsychiatric GeneticsGenetic EpidemiologyCopy Number Variants +6

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

David M. Evans, Chris C. A. Spencer, Jennifer J. Pointon, +89

Nature Genetics

InflammationRheumatologyDisease SusceptibilityAutoimmune DiseaseAllergy +9

Rare coding variants in ten genes confer substantial risk for schizophrenia

Tarjinder Singh, Timothy Poterba, David Curtis, +108

Nature

Allelic VariantPsychiatryRisk PredictionSubstantial RiskGenetics +9