Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

Xiangchun Wang, Shinya Inoué, Jianguo Gu, +23

Proceedings of the National Academy of Sciences

Inflammatory Lung DiseaseAdvanced Lung DiseaseLung InflammationImmunologyCell Death +22

Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease.

S Mizuno, Tsutomu Kurosawa, Kunio Matsumoto, +3

Journal of Clinical Investigation

Renal PathologyImmunologyRenal InflammationPathologyHgf Injection +25

Carbohydrate Binding Specificity of a Fucose-specific Lectin from Aspergillus oryzae

Kengo Matsumura, Katsuya Higashida, Hiroki Ishida, +8

Journal of Biological Chemistry

Reciprocal balance of hepatocyte growth factor and transforming growth factor-β1 in renal fibrosis in mice

Shinya Mizuno, Kunio Matsumoto, Tsutomu Kurosawa, +2

Kidney International

UrologyFibrosisHepatologyHepatocyte Growth FactorGrowth Factor-β1 +12

Fucosylation of N-Glycans Regulates the Secretion of Hepatic Glycoproteins into Bile Ducts

Tsutomu Nakagawa, Naofumi Uozumi, Miyako Nakano, +7

Journal of Biological Chemistry

Fucosylated Afp IncreasesGlycobiologyPathologyBile DuctsN-glycans Regulates +20

Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro.

Tomohiko Fukuda, Nobuaki Yoshida, Yuki Kataoka, +6

PubMed

Extra Domain BCell ProliferationCytoskeletonCell GrowthCell Specialization +16

Down-regulation of trypsinogen expression is associated with growth retardation in α1,6-fucosyltransferase-deficient mice: attenuation of proteinase-activated receptor 2 activity

Wenzhe Li, Takatoshi Nakagawa, Nobuto Koyama, +9

Glycobiology

Reduced  4 1 Integrin/VCAM-1 Interactions Lead to Impaired Pre-B Cell Repopulation in Alpha 1,6-Fucosyltransferase Deficient Mice

Wei Li, Katsuhiko Ishihara, Takafumi Yokota, +8

Glycobiology

Nephrotic Mice (ICGN Strain): A Model of Diffuse Mesangial Sclerosis in Infantile Nephrotic Syndrome

Shinya Mizuno, Yoko Mizuno-Horikawa, Bing-Fei Yue, +2

American Journal of Nephrology

Expression of α-smooth muscle actin and fibronectin in tubulointerstitial lesions of cats with chronic renal failure

Ko SAWASHIMA, Shinya Mizuno, Yoko Mizuno-Horikawa, +3

American Journal of Veterinary Research