Development of a¹⁸F‐Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging

Christoph Denk, Dennis Svatunek, Thomas Filip, +5

Angewandte Chemie International Edition

Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[11C]verapamil PET

Claudia Kuntner, Jens P. Bankstahl, Marion Bankstahl, +10

European Journal of Nuclear Medicine and Molecular Imaging

Pharmacological StudyP-glycoprotein InhibitionMedicineDose-response AssessmentNeuropharmacology +7

Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon

Andreas Walter, Perrine Paul‐Gilloteaux, Birgit Plochberger, +14

Frontiers in Physics

EngineeringMicroscopyAdvanced ImagingMultimodalityBiomedical Engineering +24

Tariquidar-Induced P-Glycoprotein Inhibition at the Rat Blood–Brain Barrier Studied with (<i>R</i>)-¹¹C-Verapamil and PET

Jens P. Bankstahl, Claudia Kuntner, Aiman Abrahim, +8

Journal of Nuclear Medicine

Tariquidar and Elacridar Are Dose-Dependently Transported by P-Glycoprotein and Bcrp at the Blood-Brain Barrier: A Small-Animal Positron Emission Tomography and In Vitro Study

Jens P. Bankstahl, Marion Bankstahl, Kerstin Römermann, +9

Drug Metabolism and Disposition

Limitations of Small Animal PET Imaging with [18F]FDDNP and FDG for Quantitative Studies in a Transgenic Mouse Model of Alzheimer’s Disease

Claudia Kuntner, Adam Kesner, Martin Bauer, +8

Molecular Imaging and Biology

Positron Emission TomographyNeurodegenerative DiseasesQuantitative StudiesAlzheimer's DiseaseEngineering +10

Design, Synthesis, and Evaluation of a Low-Molecular-Weight ¹¹C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry

Christoph Denk, Dennis Svatunek, Severin Mairinger, +6

Bioconjugate Chemistry

EngineeringImaging AgentPet-mriNaive MiceBiomedical Engineering +14

Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor

Florian F. Bauer, Claudia Kuntner, Jens P. Bankstahl, +9

Bioorganic & Medicinal Chemistry

Medicinal ChemistryThird-generation P-glycoprotein InhibitorEngineeringVivo EvaluationMedicine +11

Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted <i>In Vivo</i> Chemistry

E. Johanna L. Stéen, Jesper Tranekjær Jørgensen, Christoph Denk, +16

ACS Pharmacology & Translational Science

Synthesis and Small-Animal Positron Emission Tomography Evaluation of [¹¹C]-Elacridar As a Radiotracer to Assess the Distribution of P-Glycoprotein at the Blood−Brain Barrier

Bernd Dörner, Claudia Kuntner, Jens P. Bankstahl, +9

Journal of Medicinal Chemistry

EngineeringBrain Activity UptakePharmacotherapyExperimental PharmacologyGlioma +15